Dr. Tina Sampalis, Vice President of Research and Development for Neptune Technologies and Bioresources Inc., offers these dosage suggestions:

• If you're petite: start with a loading dose of 2 gelcaps (1 gram) per day for the first 2 weeks, then 1 gelcap (500 mg)/day for maintenance.
• If you're of average weight: a loading dose 3 gelcaps (1.5 grams)/day for the first 14-30 days, then 2 gelcaps (1 gram)/day for maintenance.
• If you're larger with a Body Mass Index (BMI) under 33: 3 gelcaps (1.5 grams)/day for the first 30 days, then 2 gelcaps (1 gram)/day.
• If your BMI is over 33, 3 gelcaps (1.5 grams)/day continuously.

As mentioned, dosage recommendations are also condition-specific. For example:

• Cholesterol Study Dosages. In a randomized 3-month study, 120 patients with blood cholesterol levels between 194-348 mg/dL were given a BMI-dependent daily dosage of 2-3 g NKO� (Group A); 1.1-5g/day (Group B); and 3g/day fish oil containing 180 mg EPA and 120 mg DHA per gram (Group C). At both lower and equal doses, NKO� was significantly more effective than fish oil for the reduction of glucose, triglyceride and LDL levels.
• Chronic Inflammation Study Dosages. A 30-day, randomized, double blind, placebo-controlled study was conducted to evaluate the effects of NKO� on C-reactive protein (CRP) in 90 patients with high CRP and chronic inflammation due to cardiovascular disease and/or rheumatoid arthritis and/or osteoarthritis. Group A received 300 mg NKO� daily and Group B, the placebo. Study results clearly indicated that only 300 mg NKO� daily significantly inhibits inflammation and reduces arthritic symptoms within a short treatment period of 7-14 days.